Effect of CPAP on 24-Hour Blood Pressure in the Excessively Sleepy Obstructive Sleep Apnea Subtype
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Device
Study Type: Observational
SUMMARY
The primary objective of this study is to determine the longer-term (6 months) effect of CPAP therapy on change in 24-hour mean blood pressure (24hMBP) in OSA subjects with the excessively sleepy symptom subtype.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:
• Age 18-75 years
• Moderate-severe OSA (defined as ODI ≥10 events/hour) via Polysomnography (PSG) or Home Sleep Apnea Study (HSAT) done based on clinical grounds
• Excessively sleepy subtype determined by patient-reported symptoms
• Willing to accept CPAP therapy
• An elevated baseline office BP defined as ≥120 or ≥80 mmHg
• Planned PAP (CPAP or bi-level PAP) treatment by treating provider
Locations
United States
Ohio
The Ohio State University - Martha Morehouse Medical Pavilion, Suite 2600
RECRUITING
Columbus
Pennsylvania
University of Pennsylvania
RECRUITING
Philadelphia
Contact Information
Primary
Alicia Gonzalez Zacarias, MD
alicia.gonzalezzacarias@osumc.edu
6143662361
Backup
Joseph Santiago, RRT
joseph.santiago@osumc.edu
6143664756
Time Frame
Start Date: 2023-02-07
Estimated Completion Date: 2028-03-01
Participants
Target number of participants: 227
Treatments
OSA subjects with the excessively sleepy symptom subtype treated with CPAP
Patients with the excessively sleepy symptom subtype who accept CPAP therapy
Related Therapeutic Areas
Sponsors
Leads: Ohio State University
Collaborators: University of Pennsylvania